Drug-resistant bacteria surge poses alarming threat in US

 September 24, 2025, NEWS

Startling data reveals a near 70% spike in infections from drug-resistant "nightmare bacteria" across the United States between 2019 and 2023.

According to AP News, the surge is largely driven by bacteria carrying the NDM gene, which renders them nearly untreatable. Only two costly antibiotics, administered via IV, can combat these infections, highlighting the dire limitations of current medical options.

The numbers paint a grim picture, with carbapenem-resistant infections rising from just under 2 per 100,000 people in 2019 to over 3 per 100,000 in 2023. More alarmingly, NDM-specific cases skyrocketed by 460%, jumping from 0.25 to 1.35 per 100,000 in the same period.

Rising Danger of NDM Gene Spread

Once considered a rare threat linked to patients treated abroad, bacteria with the NDM gene are no longer an exotic anomaly in the US. Their presence has surged over fivefold in recent years, signaling a troubling shift toward domestic proliferation.

David Weiss, an infectious diseases researcher at Emory University, called the trend "a grave danger and very worrisome." Such strong words from an expert underscore the need for immediate action, not just hand-wringing over progressive health policies that often prioritize optics over results.

Unrecognized carriers likely walk among us, posing a silent risk of community spread, according to CDC scientists. This invisible threat could turn everyday ailments into medical quagmires if we don’t rethink our approach to antibiotic stewardship.

Antibiotic Misuse Fuels the Crisis

The misuse of antibiotics, through incomplete or unnecessary prescriptions, stands as a primary culprit in this growing resistance. Germs that survive these half-measures emerge stronger, outsmarting drugs once deemed reliable.

Carbapenem-resistant bacteria, often a last-resort target for powerful antibiotics, are at the heart of this "nightmare" scenario. The CDC has long warned of their danger, yet the problem festers as overreliance on quick fixes in healthcare persists.

Dr. Jason Burnham from Washington University pointed to the COVID-19 pandemic as a likely accelerator, noting "a huge surge in antibiotic use" during that time. While the crisis demanded a rapid response, such overuse has clearly backfired, leaving us with fewer tools in the toolbox.

Data Gaps Hinder Full Understanding

The CDC’s findings, drawn from 29 states with testing and reporting systems, counted 4,341 carbapenem-resistant infections in 2023, including 1,831 NDM cases. Yet this snapshot misses major states like California and Texas, suggesting the true scope is far worse.

Burnham emphasized that the absence of data from populous regions means the total number of infections "is definitely underestimated." This blind spot in surveillance is a glaring failure, especially when decisive policy could hinge on accurate numbers.

Many hospitals lack the capacity to test for specific genetic resistance markers, and even in reporting states, cases often involve only the sickest patients. Such fragmented efforts leave us guessing at the real threat level while bacteria gain ground.

Urgent Need for Smarter Health Strategies

Dr. Maroya Walters, a CDC report author, warned that routine issues like urinary tract infections could soon defy standard treatment. This isn’t fear-mongering; it’s a call to stop coddling ineffective protocols and demand accountability in how we manage public health.

The broader issue of antimicrobial resistance, where germs outpace the drugs meant to kill them, isn’t new, yet solutions remain sluggish. We can’t afford to let ideological debates over healthcare stall the practical steps needed to curb this crisis.

This surge in "nightmare bacteria" is a wake-up call to prioritize results over rhetoric in medical policy. If we don’t act with precision and urgency, the cost will be measured not just in dollars, but in lives.

About Craig Barlow

Craig is a conservative observer of American political life. Their writing covers elections, governance, cultural conflict, and foreign affairs. The focus is on how decisions made in Washington and beyond shape the country in real terms.
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